Indications

Used for the symptomatic relief of allergic conditions and as an antitussive (cough suppressant). It is indicated for:

Allergic Reactions: Relief of symptoms associated with seasonal and perennial allergies (sneezing, runny nose, itchy/watery eyes, and itchy throat).
Urticaria and Angioedema: Management of hives and localized swelling of the skin or mucous membranes.
Antitussive: Temporary relief of dry, non-productive cough caused by minor throat and bronchial irritation (common cold or inhaled irritants).
Motion Sickness: Prevention and treatment of nausea, vomiting, and dizziness associated with motion.

Dosage and Administration

Typical concentration is 12.5 mg per 5 mL (check your specific bottle labeling for confirmation).

Adults and Children 12 years and over:
- Take 10 mL to 20 mL (25 mg to 50 mg) every 4 to 6 hours.
- Maximum Daily Dose: Do not exceed 300 mg (120 mL of 12.5 mg/5 mL syrup) in 24 hours.
Children 6 to 12 years:
- Take 5 mL to 10 mL (12.5 mg to 25 mg) every 4 to 6 hours.
- Maximum Daily Dose: Do not exceed 150 mg (60 mL of 12.5 mg/5 mL syrup) in 24 hours.
Administration: Use a calibrated measuring cup or syringe for accurate dosing. It can be taken with or without food.

Adverse Reactions

Central Nervous System: Significant drowsiness, sedation, dizziness, disturbed coordination, or headache. In some children, it may cause paradoxical excitation (restlessness).
Gastrointestinal: Dry mouth, nose, and throat; epigastric distress (stomach upset), nausea, or constipation.
Respiratory: Thickening of bronchial secretions (mucus).
Cardiovascular: Palpitations or low blood pressure (hypotension).

Important Safety Precautions

Drowsiness Warning: Diphenhydramine is a first-generation antihistamine with strong sedative effects. Strictly avoid driving, operating heavy machinery, or performing dangerous tasks while using this medication.
Alcohol Restriction: Do not consume alcohol while taking this syrup, as it will dangerously increase the sedative effects on the central nervous system.
Drug Interactions: Avoid use with other antihistamines (including topical creams/ointments) or sedatives/tranquilizers unless directed by a physician.
Pre-existing Conditions: Consult a doctor before use if you have glaucoma, asthma, emphysema, chronic bronchitis, or difficulty urinating due to an enlarged prostate.
Elderly Patients: Older adults are more sensitive to the side effects (dizziness and confusion), which may increase the risk of falls.
Pregnancy and Nursing: Consult a healthcare professional. Diphenhydramine is excreted in breast milk and may inhibit lactation or cause irritability/drowsiness in the nursing infant.

Histamox

DM Diphenhydramine Hydrochloride 50mg, 20 Capsules