DM Mebendazole Suspension, 60mL

Description

Indications

Used for the treatment of single or mixed intestinal parasite infections. It is highly effective against:

• Pinworm or Threadworm 

• Common Roundworm

• Whipworm 

• Hookworm 

Dosage and Administration

Typical concentration is 100 mg per 5 mL or 500 mg per 10 mL. Please verify the concentration on your specific bottle.

• For Pinworms (Threadworms):

  • Adults and Children 2 years and over: A single dose of 5 mL (100 mg). A second dose is usually recommended after 2 to 3 weeks to prevent re-infection.

• For Roundworms, Whipworms, and Hookworms:

  • Adults and Children 2 years and over: 5 mL (100 mg) taken twice daily (morning and evening) for 3 consecutive days.

• Administration: Shake the bottle well before each use. Use a calibrated measuring cup or spoon for accuracy. The syrup can be taken with or without food.

Adverse Reactions

Mebendazole is generally well-tolerated because very little is absorbed into the bloodstream from the gut. However, some may experience:

• Gastrointestinal: Transient abdominal pain, diarrhea, flatulence, or nausea (especially in cases of heavy parasite infestation).

• Central Nervous System: Rare instances of dizziness or headache.

• Dermatological: Very rare allergic reactions such as rash, hives, or itching.

• Serious Reactions (Rare): Neutropenia (low white blood cell count) or liver function disturbances with prolonged high-dose use.

Important Safety Precautions

• Hygiene Protocol: To prevent re-infection, it is essential to wash hands and fingernails frequently, launder bedding and towels in hot water, and treat all members of the household at the same time.

• Age Restriction: Generally not recommended for children under 2 years of age unless specifically directed by a pediatrician, as there have been rare reports of convulsions in this age group.

• Pregnancy and Nursing: Mebendazole should be avoided during the first trimester of pregnancy as it has shown embryotoxic effects in animal studies. Consult a healthcare professional if nursing.

• Drug Interactions: Concurrent use with Cimetidine may inhibit the metabolism of mebendazole in the liver, potentially increasing its plasma concentration. Avoid use with Metronidazole due to the risk of Stevens-Johnson syndrome/toxic epidermal necrolysis.

• Liver Health: Use with caution in patients with known hepatic impairment.